Saturday, 2 June 2012

Janus Kinase (JAK) Inhibitors: Competitor Analysis - Latest Report

The present Competitive Intelligence Report about new developments in the pipeline of inhibitors of the janus-associated kinase (JAK) provides a competitor evaluation in the field of active R&D projects from preclinical stages up to marketed JAK Inhibitors as of May 2012. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. The database also contains information about discontinued projects. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

As cytokines play pivotal roles in immunity and inflammation, targeting of cytokines and their receptors represents an effective means of treating such diseases. Janus kinases (JAK) are a small family of receptor-associated kinases, that together with signal transducers and activators of transcription (STAT), provide a rapid signalling pathway for cytokines. Four JAKs have been identified: JAK1, JAK2, JAK3 and tyrosine kinase 2 (Tyk2). JAK3 has attracted much attention as an anti-inflammatory drug target because of its restricted hematopoietic tissue expression and because of its specific association with the common gamma chain of the interleukin-2 (IL-2) receptor which is shared by the receptors for IL-4, IL-7, IL-9, IL-15 and IL-21.

The report includes a compilation of current active projects in research and development of selective and dual- or multi-kinase inhibitors incl. JAK inhibiton, for the treatment of myelofibrosis, polycythemia vera, psoriasis, rheumatoid arthritis and other inflammatory diseases. In addition, the report lists company-specific pipelines of JAK inhibitors. Competitor projects are listed in a tabular format providing information on:

Drug Codes,
Target / Mechanism of Action,
Class of Compound,
Company,
Product Category,
Indication,
R&D Stage and
additional comments with a hyperlink leading to the source of information.

About Competitor Analysis Series:
The Competitor Analysis Series delivers NO-FRILLS, but concise information about the pipeline of R&D projects for targets, diseases, technologies and companies at low prices. The information is provided in a tabular format and fully referenced.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/79155/janus-kinase-jak-inhibitors-competitor-analysis.html

Competitor Analysis: Staphylococcus aureus Vaccines and Therapeutics - Latest Report

The present Competitive Intelligence Report about prophylaxis and therapy of S. aureus infections provides a competitor evaluation in the field of molecules for prevention or treatment of Staphylococcus aureus infections as of May 2012. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

Staphylococcal aureus infections represent an enormous burden to public health systems. Traditionally restricted to the hospital setting as nosocomial infections, highly virulent strains have recently emerged in outside healthcare settings. Together with the increasing resistance to many antibacterials in a wide variety of staphylococcal strains, development of vaccines or specific and potent therapies for staphylococcal diseases raised increasing interest . Finding a vaccine for staphylococci is not trivial, as protective immunity to staphylococcal infections does not appear to exist at a significant degree. Promising results from novel approaches based on the combination of systematically selected antigens have been reported.

Passive immunotherapy with monoclonal therapeutic antibodies against S.aureus is another means to approach specific therapy of staphylococcal. While anti-staphylococcal purified polyclonal immunoglobulins are not recommended for prevention of staphylococcal infections in preterm or VLBW neonates, monoclonal antibodies are currently emerging and are in early development. Although not specific, bactericidal proteins and peptides with activity against S. aureus are in preclinical and clinical development. More targeted and improved antibiotics are also in development.

The report includes a compilation of currently active projects in research and development of antibodies, proteins, peptides, vaccines and small molecules for prevention and treatment of Staphylococcus aureus infections. In addition, the report lists company-specific R&D pipelines of S. aureus vaccines and therapeutics. Competitor projects are listed in a tabular format providing information on:

Drug Codes,
Target / Mechanism of Action,
Class of Compound,
Company,
Product Category,
Indication,
R&D Stage and
additional comments with a hyperlink leading to the source of information.

About Competitor Analysis Series:
The Competitor Analysis Series delivers NO-FRILLS, but concise information about the pipeline of R&D projects for targets, diseases, technologies and companies at low prices. The information is provided in a tabular format and fully referenced.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/79154/competitor-analysis-staphylococcus-aureus-vaccines-and-therapeutics-.html

Competitor Analysis: Pseudomonas aeruginosa Vaccines and Therapeutics - Latest Report

The present Competitive Intelligence Report about Pseudomonas aeruginosa Vaccines & Therapeutics provides a competitor evaluation in the field of prophylactic vaccines and therapeutic antibodies, peptides and small molecules as well as DNA-, RNA- and microorganism-based therapies against infection with Pseudomonas aeruginosa as of May 2012. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

Pseudomonas aeruginosa is an opportunistic gram-negative bacteria that lives in soil, water, and even in environments like hot tubs. For most healthy people, this bacteria seldom poses a problem. Pseudomonas aeruginosa is much more dangerous to populations who have weak immune systems, the elderly, and those who have been hospitalized for long periods of time. People with cystic fibrosis and with full-blown AIDS frequently die from infections created by the bacteria. Hospital-acquired pneumonia, particularly ventilator-associated pneumonia , causes considerable morbidity and mortality despite antimicrobial therapy and advances in supportive care. It is the second most frequent nosocomial infection and is the major cause of death among hospital-acquired infections.

The report includes a compilation of currently active projects in development of vaccines, antibodies, peptides and small molecules as well as of DNA-, RNA- and microorganism-based therapies targeting Pseudomonas aeruginosa for prophylaxis and treatment of P. aeruginosa infection. In addition, the report lists company-specific R&D pipelines of Pseudomonas aeruginosa Vaccines & Therapeutics. Competitor projects are listed in a tabular format providing information on:

Drug Codes,
Target / Mechanism of Action,
Class of Compound,
Company,
Product Category,
Indication,
R&D Stage and
additional comments with a hyperlink leading to the source of information.

About Competitor Analysis Series:
The Competitor Analysis Series delivers NO-FRILLS, but concise information about the pipeline of R&D projects for targets, diseases, technologies and companies at low prices. The information is provided in a tabular format and fully referenced.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/79153/competitor-analysis-pseudomonas-aeruginosa-vaccines-and-therapeutics-.html

Friday, 1 June 2012

Online Travel Market in China 2012 - Latest Report

With the world’s largest internet user base of over 450 mn, the online travel market in China is set to gain immense popularity within the local tourist community.

The report begins with the market overview section, providing a snapshot of online travel market in Asia, which is expected to be the most important driver affecting the overall Asian travel market in 2012. This is followed by the online travel market in China, with details on the domestic online travel market size in terms of online travel market value and its growth. China’s online travel market is estimated to grow at a CAGR of 35.2% annually up to 2012. It also mentions the size of the online travel booking consumer base and its growth over past few years. The share of population indulging in different types of online travel booking services has been included in this section. Further, the report provides an illustration of the online travel industry business model wherein it depicts the structure of the market, followed by the description of various kinds of services offered by the online travel industry and the corresponding players. Another detailed illustration about the commission charged by the players operating in the online travel market has been included.

Factors driving the growth of online travel market in China are also explained in detail. Increasing internet usage coupled with growth in mobile internet subscribers is providing impetus to the growth in online travel market. China has the world’s largest internet user base, representing 23% of the global online population. Mobile internet users have been growing at a CAGR of 45%. Rising middle class and increasing income will lead to increasing demand for online travel booking services. Rise in credit card holders will allow online travel agencies (OTAs) to increase their customer base. Credit card holders have grown at a CAGR of 24%. Growth in tourism along with reduced visa restrictions on Chinese Travelers provides growth prospects for the market. Outbound tourists are expected to grow at a CAGR of 16.9% up to 2012. Changing consumer lifestyle and untapped market potential provide opportunities for the players to capitalize upon.

The players operating in the market also face challenges which are impeding their development and growth prospects. Increasing competition and lack of automation have been identified as major challenges, threatening the position of existing market leaders. Regulation on foreign-invested travel agency restricts the entry of the foreign players in the domestic online travel industry.

The report also mentions the government regulations adopted for supporting the sustainable development of the overall online travel industry. It provides a detailed illustration of the new travel agency regulations benefiting the foreign players alongwith key penalties charged for misconduct by the OTAs.

Emerging trends in the online travel market include widening service offerings by the players, coordination with online communities and growing investments for facilitating the overall functioning and development of the market.
Mergers and acquisitions section covers the key deals taken place in the online travel space of China. This section includes the announced date, closing date, target, buyer/investor, seller and deal size.

The competition section outlays the competitive landscape of the online travel industry in China briefing about the domestic and foreign players existing in the market. This section provides a three dimensional analysis of domestic key players’ revenues, profits and market capitalization. The report also features brief profiles of major domestic and foreign players in the market and a snapshot of their corporation, financial performance along with the key financial ratios, business highlights and their product portfolio providing an insight into the existing competitive scenario.

Some of the key statistics or factors impacting the online travel market in China covered in the report includes factors impacting the Asian travel industry, domestic market size, online travel booking consumer base, online travel booking activities, online travel market structure, online travel business model and commission charged, internet population and penetration, share of internet users indulged in online travel booking, mobile internet users, share of mobile internet users accessing online travel booking services, share of Chinese urban households, Share of preferred leisure activities, urban consumer spending, urban disposable income, Share of total spending including basic and discretionary, growth in credit card holders, consumer credit card spending, rise in outbound tourism and inbound tourism, government regulatory framework, services offered, tie up with online communities and investments in the online travel market.

Key takeaway section summarizes the entire market in terms of opportunities, trends and challenges persisting in the online travel market in China.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/78711/online-travel-market-in-china-2012.html

Mobile Commerce Market in India 2012 - Latest Report

Mobile Commerce is the activity of commencing commercial transactions between both B2C and B2B entities via mobile devices. Indian retail market has experienced high growth over the last decade with a gradual shift towards modern retailing formats. With growing numbers of mobile devices and mammoth wireless subscriber base, the focus is slowly shifting to mobile platforms. Leveraging on enhanced reach like MVAS and diverse features like of e-commerce, m-commerce is poised for greater adoption across India, in the coming years.

“Although mobile commerce market in India is in nascent stage, m-payment and m-banking segments have shown significant growth over the last few years. Initiative taken by the government and financial organizations to reach India’s un-banked population can ensure tremendous growth in the latter segments. There are around 600,000 territories that require banking facilities but only around 89,000 bank branches are there in the country.” says Mr. Kalyan Banga, Product Manager at Netscribes.

The report begins with ‘Introduction’ section covering overview of mobile commerce or m-commerce which provides basic idea of the segment, essential features of m-commerce system which describes the idle features that should exist in an m-commerce solution. Retail ecosystem with m-commerce delivers a comparison between traditional, modern and m-commerce based retail supply chain in the form of a diagram.

The ‘Mobile Commerce Overview’ section elaborates global & domestic market state of m-commerce. It is accompanied by a plethora of statistical information regarding major m-commerce segments in various countries including in India, such as global trend, state in major countries, global m-payment market size and growth, domestic market size of M-Payment and projection of the same in the coming years and, other related information. Major MVAS delivery platforms for m-commerce services are also covered in the section with details regarding each of the components’ cost, application and usage trends. “Analysis show, P2P transaction, utility bill payments, mobile recharges and, at times, P2M transactions are the ones for which mobile payments are used in India predominantly” noted Kalyan. The section continues with mobile commerce value chain diagram along with a comparison between the demand and supply side of m-commerce system. The section ends with SWOT analysis of the Indian m-commerce market.

It is followed by ‘Drivers & Challenges’ section elaborating the major furtherance & impediments for m-commerce market in India. Both the ‘drivers’ and ’challenges’ are equally stressed upon to provide clear idea regarding the probable obstacles and rewards in the line of business and help vendors take necessary measures. “With huge mobile subscriber base across India and increasing trend of shopping over internet amongst youth has set the stage for m-commerce in India, but low awareness and security concerns are delaying significant adoption of the same” added Kalyan.

The report continues with ‘Market Opportunity’ section where potential verticals for m-commerce solutions in India are elaborated. Specific verticals have been highlighted with information regarding each of their market state and opportunity areas for m-commerce. The section also consists of a ‘Vendor Opportunities’ stressing on specific prospective segments and areas for mobile commerce. The section consists of statistical charts and pictorial representation for profound knowledge.

In the ‘M-Commerce Player Profiles’ section, the key m-commerce service providers are profiled. It provides information such as corporate & business highlights covering operational & recent information regarding each company’s contact information, location, key product and service offerings and key contacts. It also provides financial performance for a period of time including revenue and profit, key ratios, financial summary and key financial performance indicators. Key business segment and key geographic segment for each player are provided as well to provide further clear idea regarding the companies.

Next the recent developments and prominent trends in the market are illuminated under ‘Market Trends’ section.

The report concludes with the section ‘Strategic Recommendation’ which is derived after a comprehensive analysis of the market state & scope. It suggests key strategic moves which can help enhance and accelerate adopting of MVAS. “M-commerce services stand to gain immense traction in India, if rural and sub-urban population and their needs and preferences are properly catered. For urban market, which is being driven largely by youth, players should develop visually appealing interactive and well organized m-commerce solutions”, said Kalyan.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/78710/mobile-commerce-market-in-india-2012.html

PVC Pipes market in India 2012 - Latest Report

The Indian PVC pipes market is growing at a healthy rate due to tremendous government spending on infrastructure. The durability of PVC pipes along with the various applications makes it the preferred option over conventional pipes. Furthermore, the construction sector and the agricultural sector are expected to boost demand for PVC pipes in the future.

The report begins with an introduction to the global PVC market. It provides an insight into India’s position in the global market with regards to lower per capita consumption creating strong opportunity in the domestic market. It also indicates the growing usage of PVC for making PVC pipes. The market overview section estimates the market size of the Indian PVC pipe market and also provides the growth rate. Segmented share of PVC pipes in the total pipes market is highlighted. Porter’s analysis helps understand the dynamics in the PVC pipes market in India. The import-export section covers the quantity of PVC pipes imported and exported from India in the last four years. The slide also mentions the segmented share of import and export by major countries.

Drivers identified include growing demand of the PVC pipes due to tremendous investment by the government on infrastructure. Furthermore, growth in real estate also adds to the demand. It has also been found that agricultural sector uses PVC pipes in a big way for all their agricultural needs. The subsidies and investments doled out by the government should bolster the demand of PVC pipes. The beneficial properties of PVC boosts the demand for PVC pipes compared to other types of pipes which also gives rise to replacement demand. One of the challenges the PVC pipe market is facing is the increasing trend of crude oil prices which squeezes the profit margin of the manufacturers. The increase in price cannot be passed on to the customer due to tremendous competition. As a result, low profit margins poses as a challenge to the organized sector. The primary trends in the PVC pipes market include popularity of CPVC pipes as they have many beneficial properties and find higher application in both industrial and household uses. Since domestic demand is always very high, India has to import PVC pipes from other countries. In addition, many players are increasing their PVC pipes production capacity to meet demand.

The competition section begins with a bubble chart which provides the relative positions of the players based on their revenue, net profit and asset value or market capitalization/ asset value. The major players in the market have been profiled which includes a financial summary for each of the players. Key ratios and key contacts are also listed. The last section offers strategic recommendations for the players in the PVC pipes market.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/78709/pvc-pipes-market-in-india-2012.html

Printers Market 2012 - Latest Report

Printers market in India is currently undergoing through a phase wherein the market can be characterized with steady growth and a cut-throat competition amongst players operating in the market space. Prime factors influencing growth in the market happen to be the prevailing of major active industry verticals and the exponential growth in content creation. Further, the presence of a massive SMB population also boosts the market by a large extent, wherein SMBs shell out a decent proportion of their revenues for computational purchases.

The market comprises of multiple segments including inkjet, dot matrix and laser printers. “Ongoing advancement in the field of technology has resulted in the evolution of state-of-the art multifunction devices which are capable of facilitating several tasks and it is this device which is gaining a significant momentum in the market,” says Mr. Kalyan Banga, Product Manager at Netscribes. An array of factors including high content generation, enterprise mobility, declining prices and the huge PC base in India basically propels the market forward. An ongoing tendency to adopt inkjet multifunction devices, cloud printing, green printing and managed printing services is on the rise in the India.

The report primarily deals with three categories of printers comprising of inkjet, dot matrix and laser printers and begins with an introduction section, defining the market scope of the report. The section briefly discusses the working model of each of these printers. Market overview section in the report lists and explains the various reasons propelling the market. It also mentions the key initiatives taken by the Government of India to stimulate the market. In terms of market size, the report provides graphical representation of the printer shipment in India in context with the overall Indian as well as the SMB printer market. Moving along, the section also lists down the key purchase decisions of customers so as to give a better idea about the general mind set of prospective customers. The section also features a separate portion on competitive breakdown wherein the market share of the top vendors and major vendor’s market share across each printer category is illustrated, which in turn helps readers to understand the current competitive landscape in the India printer market. This section further elaborates on the SMB market scenario and lists down crucial aspects such as the key strategic decisions and purchase preference of SMBs. An illustration of purchase decision making matrix is provided which helps in understanding the process in which any IT purchase decision is executed. This matrix can be effectively utilized by vendors to generate strategies for better sales in the SMB segment. Further, the SMB market overview section lists down the top 40 cities in India which has a significant proportion of SMBs present and hence a sizeable number of printers are shipped to these cities has been provided in a tabulated manner and thus can be used by printer manufacturers and distributors to develop their city based strategies and expansion plans in India. A commentary on the top 40 cities vendor opportunity brings forth value added insights about the SMB market space, wherein it enlightens the reader on aspects such as the largest printer consuming industry verticals and printer friendly clusters in India amongst others.

Import and Export overview section talks about the overall EXIM trade that has been conducted since 2006-08. It graphically lists the history of printer EXIM in India and chalks out some key aspects from the data which in turn reflects the past condition of the printers market in India.

Go-to-Market strategy section has been derived after a thorough analysis of the market and comprises of essential strategies which can be implemented by vendors so as to facilitate better revenue generation and successful business operations. An analysis of the factors influencing growth in the market explains growth factors such as huge PC base, declining prices, increased disposable income and high content generation. “Primarily, the PC-printer ratio still has a wide gap and it is this gap which is creating a constant pull for printers in the market,” noted Kalyan.

Trends section in the report talks about the emerging trends in the market. “With the advent of technology, both SMBs and large enterprises are shifting their focus on adopting modern and profitable technologies such as green printing, cloud printing and managed printers services,” noted Kalyan. The section in the report explains the trends in details along with their benefits, challenges and illustration of working models, for the better understanding of readers. “Currently, the market is flooded with foreign players who have managed to garner a significant market share in India are continually increasing the pressure on their counterparts in the market,” noted Kalyan.

Key printer vendors have been profiled in details within the report which enables readers to get a clear picture of the current competitive scenario. The section lists the basic details of the players such as corporate information, business highlights and key members. The section also features financial analysis of key vendors which in turn provides us with the financial health of players. It also features SWOT analysis of individual printer manufacturer which in turn provides an extended value addition to the report.

The report concludes with a section on strategic recommendations which comprises of an analysis of the growth strategies of the printer market in India. “Pushing the sales of color printers and building a better foothold in the unsaturated markets are the two essentials strategies which are expected to propel better printer sales,” noted Kalyan.

To view the detailed table of contents for this report please visit: http://www.reportstack.com/product/78708/printers-market-2012.html